Covid-19 Treatment Protocol by Dr. Zev Zelenko

Posted by Zev Vladimir Zelenko, M.D.

Fundamental Principles

Treat patients based on clinical suspicion as soon as possible, preferably within the first 5 days of symptoms. Perform PCR testing, but do not withhold treatment pending results.

Risk Stratify Patients

  • Low risk patient – Younger than 45, no comorbidities, and clinically stable
  • High risk patient – Older than 45, younger than 45 with comorbidities, or clinically unstable

Treatment Options

Low risk patients
  • Supportive care with fluids, fever control, and rest
  • Elemental Zinc 50mg 1 time a day for 7 days
  • Vitamin C 1000mg 1 time a day for 7 days
  • Vitamin D3 5000iu 1 time a day for 7 days
Optional over the counter options
  • Quercetin 500mg 2 times a day for 7 days or
  • Epigallocatechin-gallate (EGCG) 400mg 1 time a day for 7 days
Moderate / High risk patients
  • Elemental Zinc 50-100mg once a day for 7 days
  • Vitamin C 1000mg 1 time a day for 7 days
  • Vitamin D3 10000iu once a day for 7 days or 50000iu once a day for 1-2 days
  • Azithromycin 500mg 1 time a day for 5 days or
  • Doxycycline 100mg 2 times a day for 7 days
  • Hydroxychloroquine (HCQ) 200mg 2 times a day for 5-7 days and/or
  • Ivermectin 0.4-0.5mg/kg/day for 5-7 days Either or both HCQ and IVM can be used, and if one only, the second agent may be added after about 2 days of treatment if obvious recovery has not yet been observed etc.
Treatment Options
  • Dexamethasone 6-12mg 1 time a day for 7 days or
  • Prednisone 20mg twice a day for 7 days, taper as needed
  • Budesonide 1mg/2cc solution via nebulizer twice a day for 7 days
  • Blood thinners (i.e. Lovenox, Eliquis, Xarelto, Pradaxa, Aspirin)
  • Colchicine 0.6mg 2-3 times a day for 5-7 days
  • Monoclonal antibodies
  • Home IV fluids and oxygen

TRY TO KEEP PATIENTS OUT OF THE HOSPITAL

  • https://www.sciencedirect.com/science/article/pii/S0924857920304258
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/
  • https://pubs.acs.org/doi/10.1021/jf5014633
  • https://vdmeta.com/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318306/
  • https://pubs.acs.org/doi/10.1021/jf5014633
  • https://www.sciencedirect.com/science/article/pii/S0924857920304258
  • https://ivmmeta.com/
  • https://www.nejm.org/doi/full/10.1056/NEJMoa2021436
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392554/
  • https://www.medrxiv.org/content/10.1101/2021.01.26.21250494v1

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Protocol PDF
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https://vladimirzelenkomd.com/treatment-protocol/